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The Everyday
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Everyday life and news, connected to
peptide science through clear sources.
On your reading list
Thoughtful places to start.
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IV NAD+ After a Heart Attack? What a New Hospital Trial Found
A 120-patient trial gave NAD+ by vein for a week after emergency stenting for a heart attack. Heart pumping was slightly better at 30 days, but repeat heart events at…
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Vitamin B3 for Glaucoma? What the Nicotinamide Trials Show So Far
Small placebo-controlled trials found short-term gains in some retinal function tests when people with glaucoma took nicotinamide, an NAD+ precursor, but no trial has shown it slows glaucoma, high trial…
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Gained Weight on a Newer HIV Pill? What Tesamorelin Data Show
Integrase-inhibitor HIV regimens are linked to weight gain. In a small subgroup of a year-long placebo trial, tesamorelin cut deep belly fat and liver fat in people on these drugs…
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Kidney Disease and NAD+ Supplements: What the Trials Have Shown
In a small placebo-controlled trial in moderate kidney disease, nicotinamide riboside shifted blood chemistry but did not improve stamina, and kidney function held steady. Larger nicotinamide trials in kidney patients…
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Stopping Egrifta: Deep Belly Fat Built Back Up in the Trials
In tesamorelin trials for HIV-related belly fat, visceral fat reaccumulated after patients switched to placebo, while those who stayed on it kept the drop for a year. Six months was…
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TB Treatment and Vitamin D: The LL-37 Idea Fell Short in Trials
Vitamin D helps immune cells make LL-37, which attacks the TB germ in the lab. But in trials it did not prevent TB infection in more than 10,000 children, and…
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An Old Hepatitis C Add-On: What the Thymosin Alpha-1 Trials Showed
Thymosin alpha-1 was tested for hepatitis C from the 1990s to 2012, alone and with interferon. The largest trial, 552 patients, found nearly the same cure rate with or without…
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Can an NAD+ Booster Help a Weak Heart? A Small Placebo Trial Checked
In a 12-week placebo-controlled trial of 30 people with heart failure, nicotinamide riboside was well tolerated and roughly doubled blood NAD+, but walking distance, quality of life and heart pumping…
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Is Vyleesi a Brain Drug? What a Placebo Brain-Scan Study Found
In a placebo-controlled crossover study of 31 women with low desire, a Vyleesi shot raised reported desire over the next day and changed brain responses to erotic videos. It explains…
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Can Vitamin D Help Eczema by Raising the Skin Peptide LL-37?
Vitamin D can raise cathelicidin, the source of LL-37, in eczema skin, but a 101-child placebo trial found no change in LL-37 or severity. A winter trial in Mongolia did…
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Fatty Liver Without HIV: A Year of Tesamorelin on Scans and Biopsies
A one-year placebo trial in 51 adults with obesity and fatty liver but no HIV posted results: liver fat on scans dipped with tesamorelin, but biopsy scores for inflammation and…
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Will Adding Thymosin Alpha-1 to Entecavir Lower Liver Cancer Risk?
In 690 people with hepatitis B cirrhosis on entecavir, a year of added thymosin alpha-1 did not lower liver failure, liver cancer or death. Early lab gains in smaller trials…
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